B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production
نویسندگان
چکیده
منابع مشابه
B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production
A small subset of B cells, termed B-1 cells, with developmental origins, phenotypes, and functions that are distinct from those of conventional B cells exist in mice. It contributes the vast majority of spontaneously produced "natural" IgM. Natural IgM is constitutively produced, even in the absence of microbiota, and fulfills many distinct functions in tissue homeostasis and host defense. B-1 ...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2016
ISSN: 1664-3224
DOI: 10.3389/fimmu.2016.00324